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Efficacy and tolerability of an endogenous metabolic modulator (AXA1125) in fatigue-predominant long COVID: a single-centre, double-blind, randomised controlled phase 2a pilot study

Van WeldenSSelfridgeACHindryckxP

We found that fat transplantation significantly ameliorated hyperglycemia in Insr P1195L/ +/HFD mice

Aguilar, G

In their study, human-derived monocytes were treated with either PMA, pharmacologic G6PD inhibitor 6-AN, G6PD-silencing siRNA, siRNA + hyperglycemia, or hyperglycemia alone and then inspected for changes in monocyte polarization without an immunogenic stimulus